Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670109 | 0.83 | — | — | |
| SCHEMBL19218136 | 0.80 | EPHX1 (0.31) | — | |
| SCHEMBL13608953 | 0.77 | — | — | |
| SCHEMBL657653 | 0.77 | HSD11B1 (0.35) | TP53CYP3A4MAPTPOLBTDP1 | |
| SCHEMBL320036 | 0.75 | MEN1 (0.34) | CYP2C19 | |
| SCHEMBL10313054 | 0.74 | POLB (0.33) | POLBTDP1 | |
| SCHEMBL19218149 | 0.71 | EPHX1 (0.30) | — | |
| SCHEMBL6789531 | 0.71 | ATM (0.41) | CYP3A4MAPTCYP2C19POLB | |
| SCHEMBL46361 | 0.71 | KMT2A (0.34) | TP53MAPTPOLB | |
| SCHEMBL13500408 | 0.71 | MEN1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785934-A1 | SUBSTITUTED SPIROALKYLAMINO AND SPIROALKOXY-HETEROCYCLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011924-A1 | SUBSTITUTED SPIROALKYLAMINO AND SPIROALKOXY-HETEROCYCLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-04-25 | — | — | WO | disclosed |