Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564480 | 0.90 | TACR1 (0.51) | TACR1 | |
| SCHEMBL8559555 | 0.90 | TACR1 (0.40) | TACR1 | |
| Hydrochloric Acid SCHEMBL8560679 | 0.90 | TACR1 (0.50) | TACR1 | |
| SCHEMBL8806614 | 0.89 | TACR1 (0.42) | TACR1 | |
| SCHEMBL8812887 | 0.89 | TACR1 (0.42) | TACR1 | |
| SCHEMBL8563009 | 0.88 | TACR1 (0.51) | TACR1 | |
| SCHEMBL8561114 | 0.88 | TACR1 (0.40) | TACR1 | |
| SCHEMBL8558335 | 0.88 | TACR1 (0.53) | TACR1 | |
| SCHEMBL8559848 | 0.88 | TACR1 (0.40) | TACR1 | |
| Hydrochloric Acid SCHEMBL8566329 | 0.87 | TACR1 (0.52) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775140-A1 | SPIRO-SUBSTITUTED AZACYCLIC DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LTD. (GB) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005203-A1 | SPIRO-SUBSTITUTED AZACYCLIC DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 1996-02-22 | — | — | WO | disclosed |