Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808316 | 0.83 | TSHR (0.51) | MEN1KMT2AMAPTHTTTHRB | |
| SCHEMBL8807581 | 0.78 | CYP3A4 (0.63) | MEN1KMT2AMAPTHTTTHRB | |
| SCHEMBL8790688 | 0.76 | ABCG2 (0.70) | MEN1KMT2AMAPTABCG2ADORA3 | |
| SCHEMBL8809581 | 0.76 | CYP3A4 (0.60) | MEN1KMT2AMAPTHTTNPC1 | |
| SCHEMBL8807078 | 0.76 | MAPT (0.46) | MEN1KMT2AMAPTHTTTHRB | |
| SCHEMBL8807062 | 0.76 | OPRM1 (0.49) | MEN1KMT2AMAPTHTTTHRB | |
| SCHEMBL8807073 | 0.75 | KDR (0.48) | MEN1KMT2AMAPTHTTTHRB | |
| SCHEMBL8789125 | 0.71 | ABCG2 (0.65) | MEN1KMT2AMAPTABCG2ADORA3 | |
| SCHEMBL29386442 | 0.71 | HTT (0.67) | MEN1KMT2AMAPTHTTTHRB | |
| SCHEMBL8836072 | 0.70 | ABCG2 (0.66) | MEN1KMT2AMAPTABCG2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663179-A | CAN SENSITIZE MULTIDRUG RESISTANT CANCER CELLS TO CHEMOTHERAPEUTIC AGENTS | LABORATOIRES GLAXO SA (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |