SCHEMBL880870

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL880856	0.93	CYP11B1 (0.38)	TDP1POLBCYP11B1CA12CA1
	SCHEMBL16405423	0.90	POLB (0.41)	TDP1POLBCNR1CNR2ALDH1A1
	SCHEMBL854367	0.89	CA12 (0.45)	TDP1POLBCA12CA1CA2
	SCHEMBL15479847	0.89	TDP1 (0.44)	TDP1POLBCNR1CNR2ALDH1A1
	SCHEMBL29476054	0.89	CA12 (0.45)	TDP1POLBCA12CA1CA2
	SCHEMBL880868	0.89	TDP1 (0.44)	TDP1POLBCNR1CNR2ALDH1A1
	SCHEMBL10130243	0.89	CYP11B1 (0.38)	TDP1CYP11B1CA12CA1CA2
	SCHEMBL880872	0.89	TDP1 (0.43)	TDP1POLBCNR1CNR2ALDH1A1
	SCHEMBL880875	0.89	TDP1 (0.43)	TDP1POLBCNR1CNR2ALDH1A1
	SCHEMBL12088908	0.89	POLB (0.42)	TDP1POLBCNR1CNR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.