SCHEMBL8808707

SCHEMBL8808707

O=C(O)COc1cccc2c1CCC(C=CCn1cc(Cc3ccccc3-c3cccnc3)cn1)C2

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 18/20 0.46
PTGDR Q13258 8/20 0.45
TBXAS1 P24557 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8814204 0.90 PTGIR (0.53) PTGIRPTGDR
SCHEMBL8413362 0.87 PTGIR (0.62) PTGIRPTGDR
SCHEMBL8813306 0.85 PTGIR (0.45) PTGIRPTGDRTBXAS1
SCHEMBL8810877 0.81 PTGIR (0.65) PTGIRPTGDRTBXAS1
SCHEMBL8808701 0.81 PTGIR (0.65) PTGIRPTGDRTBXAS1
SCHEMBL8411299 0.80 PTGIR (0.41) PTGIRPTGDRTBXAS1
SCHEMBL8412661 0.78 PTGIR (0.62) PTGIRPTGDR
SCHEMBL8520476 0.77 PTGIR (0.64) PTGIRPTGDRTBXAS1
SCHEMBL8414221 0.77 PTGIR (0.61) PTGIRPTGDR
SCHEMBL8811346 0.77 PTGIR (0.66) PTGIRPTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0548949-B1 Fused benzeneoxyacetic acid derivatives ONO PHARMACEUTICAL CO (JP) 1997-09-17 EP claimed
EP-0548949-B1 Fused benzeneoxyacetic acid derivatives ONO PHARMACEUTICAL CO (JP) 1997-09-17 EP disclosed
US-5389666-A Administering for treatment and prevention of thrombosis, arteriosclerosis, ischemic heart diseases, gastric ulcer or hypertension ONO PHARMACEUTICAL CO., LTD. (JP) 1995-02-14 US disclosed
EP-0548949-A2 Fused benzeneoxyacetic acid derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1993-06-30 EP disclosed