Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 13/20 | 0.64 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520473 | 0.82 | PTGIR (0.89) | PTGIRTBXAS1KDM4C | |
| SCHEMBL8411299 | 0.80 | PTGIR (0.41) | PTGIRTBXAS1PTGDRPLA2G1B | |
| SCHEMBL8413362 | 0.80 | PTGIR (0.62) | PTGIRPTGDR | |
| SCHEMBL8411192 | 0.79 | PTGIR (0.61) | PTGIRTBXAS1PTGDRPLA2G1B | |
| SCHEMBL8411068 | 0.78 | PTGIR (1.00) | PTGIRTBXAS1KDM4C | |
| SCHEMBL8808707 | 0.77 | PTGIR (0.46) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8410718 | 0.74 | PTGIR (0.90) | PTGIRTBXAS1 | |
| SCHEMBL8410702 | 0.73 | PTGIR (0.60) | PTGIRTBXAS1 | |
| SCHEMBL8633392 | 0.73 | PTGIR (0.72) | PTGIRTBXAS1KDM4C | |
| SCHEMBL8411096 | 0.73 | PTGIR (0.90) | PTGIRTBXAS1PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |