Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.66 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690456 | 1.00 | PARP1 (0.66) | PARP1HPGDMEN1KMT2AHTT | |
| SCHEMBL31005261 | 0.88 | PARP1 (0.52) | PARP1HPGDMTOR | |
| SCHEMBL31005256 | 0.88 | PARP1 (0.62) | PARP1HPGDMTOR | |
| SCHEMBL31005240 | 0.88 | PARP1 (0.64) | PARP1HPGD | |
| SCHEMBL31005223 | 0.88 | PARP1 (0.52) | PARP1HPGDMTOR | |
| SCHEMBL31005255 | 0.88 | PARP1 (0.64) | PARP1HPGD | |
| SCHEMBL8809703 | 0.88 | HPGD (0.53) | PARP1HPGDMEN1KMT2AMTOR | |
| SCHEMBL8809700 | 0.88 | HPGD (0.53) | PARP1HPGDMEN1KMT2AMTOR | |
| SCHEMBL31005242 | 0.86 | PARP1 (0.50) | PARP1HPGD | |
| SCHEMBL31005252 | 0.86 | GSK3B (0.55) | PARP1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |