Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 9/20 | 0.51 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.47 |
| ▸ | NAT1 | P18440 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809700 | 1.00 | HPGD (0.53) | HPGDMTORPARP1TTRMEN1 | |
| SCHEMBL8690456 | 0.88 | PARP1 (0.66) | HPGDMTORPARP1TTRMEN1 | |
| SCHEMBL8808787 | 0.88 | PARP1 (0.66) | HPGDMTORPARP1TTRMEN1 | |
| SCHEMBL8685962 | 0.84 | PARP1 (0.66) | HPGDPARP1TTRMEN1AKR1B1 | |
| SCHEMBL8685959 | 0.84 | PARP1 (0.66) | HPGDPARP1TTRMEN1AKR1B1 | |
| SCHEMBL8813387 | 0.83 | PARP1 (0.58) | HPGDMTORPARP1TTRMEN1 | |
| SCHEMBL8813380 | 0.83 | PARP1 (0.58) | HPGDMTORPARP1TTRMEN1 | |
| SCHEMBL8688052 | 0.83 | TTR (0.53) | PARP1TTRMEN1AKR1B1KMT2A | |
| SCHEMBL8811211 | 0.81 | PARP1 (0.51) | PARP1TTRMEN1AKR1B1KMT2A | |
| SCHEMBL8685422 | 0.81 | PARP1 (0.51) | PARP1TTRMEN1AKR1B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |