Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809211 | 0.90 | MAOB (0.54) | MRGPRX4MAOB | |
| SCHEMBL8812284 | 0.85 | CYP19A1 (0.41) | MRGPRX4CYP19A1FNTAFNTBPGGT1B | |
| SCHEMBL8808372 | 0.85 | CSF1R (0.36) | XDHMAOB | |
| SCHEMBL8810273 | 0.84 | MRGPRX4 (0.43) | MRGPRX4 | |
| SCHEMBL8807665 | 0.84 | — | — | |
| SCHEMBL8807149 | 0.82 | NPC1 (0.48) | MRGPRX4CYP3A4 | |
| SCHEMBL8808406 | 0.82 | MRGPRX4 (0.41) | MRGPRX4 | |
| SCHEMBL8810163 | 0.82 | MRGPRX4 (0.41) | MRGPRX4 | |
| SCHEMBL8814947 | 0.81 | AR (0.40) | MRGPRX4MAOBCYP19A1 | |
| SCHEMBL8812391 | 0.77 | XDH (0.38) | XDHMRGPRX4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805802-A1 | SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS | RHONE-POULENC RORER LIMITED (GB) | 1997-11-12 | — | — | EP | claimed |
| WO-1996022978-A1 | SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS | RHONE POULENC RORER LIMITED (GB) | 1996-08-01 | — | — | WO | claimed |