Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.64 |
| ▸ | HTR2B | P41595 | 3/20 | 0.64 |
| ▸ | F2 | P00734 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | MASP2 | O00187 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5900833 | 0.99 | HTR2C (0.62) | HTR2CHTR2BF2KDM4EHDAC1 | |
| Hydrochloric Acid SCHEMBL5900838 | 0.99 | HTR2C (0.62) | HTR2CHTR2BF2KDM4EHDAC1 | |
| SCHEMBL6606024 | 0.93 | F2 (0.61) | HTR2CHTR2BF2MASP2 | |
| SCHEMBL23840789 | 0.85 | F2 (0.72) | F2MASP2 | |
| SCHEMBL23793372 | 0.85 | F2 (0.59) | HTR2CHTR2BF2MASP2 | |
| SCHEMBL17268026 | 0.84 | HTR2C (0.70) | HTR2CHTR2BKDM4EHDAC1HDAC3 | |
| SCHEMBL8305420 | 0.83 | PRCP (0.47) | HTR2CHTR2BF2KDM4EHDAC1 | |
| SCHEMBL24653087 | 0.81 | HTR2C (0.70) | HTR2CHTR2BKDM4EHDAC1HDAC3 | |
| SCHEMBL24648976 | 0.81 | HTR2C (0.70) | HTR2CHTR2BKDM4EHDAC1HDAC3 | |
| SCHEMBL21206860 | 0.81 | HTR2C (0.70) | HTR2CHTR2BKDM4EHDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355674-B1 | OLIGO ALKYLENE GLYCOL OR POLYALKYLENE GLYCOL-COUPLED THROMBIN INHIBITORS | JENAFFIN GMBH (DE) | 2010-10-27 | — | — | EP | disclosed |
| WO-1996025426-A9 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | — | 1997-06-12 | — | — | WO | disclosed |