Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809131 | 0.83 | HTR2C (0.64) | HTR2CHTR2BKDM4EF2HDAC1 | |
| SCHEMBL8305423 | 0.83 | PRCP (0.47) | PRCPST14HTR2CHTR2BITGB3 | |
| Hydrochloric Acid SCHEMBL5900838 | 0.82 | HTR2C (0.62) | HTR2CHTR2BKDM4EF2HDAC1 | |
| Hydrochloric Acid SCHEMBL5900833 | 0.82 | HTR2C (0.62) | HTR2CHTR2BKDM4EF2HDAC1 | |
| SCHEMBL8548940 | 0.77 | PRCP (0.62) | PRCPHTR2CHTR2BKDM4E | |
| SCHEMBL6606024 | 0.76 | F2 (0.61) | ST14HTR2CHTR2BF2 | |
| SCHEMBL23840789 | 0.72 | F2 (0.72) | F2 | |
| SCHEMBL10709444 | 0.70 | MEN1 (0.60) | PRCPHTR2CHTR2B | |
| SCHEMBL10706722 | 0.70 | MEN1 (0.60) | PRCPHTR2CHTR2B | |
| SCHEMBL5498791 | 0.70 | PRCP (0.68) | PRCPHTR2CHTR2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944618-A1 | NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE | FOURNIER INDUSTRIE ET SANTE (FR) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998024783-A1 | NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE | FOURNIER INDUSTRIE ET SANTE (FR) | 1998-06-11 | — | — | WO | disclosed |