Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4211452 | 0.83 | NPC1 (0.60) | RAB9ANPC1RECQLSMN1; SMN2L3MBTL1 | |
| SCHEMBL4211458 | 0.83 | NPC1 (0.60) | RAB9ANPC1RECQLSMN1; SMN2L3MBTL1 | |
| SCHEMBL3808783 | 0.83 | NPC1 (0.60) | RAB9ANPC1RECQLSMN1; SMN2L3MBTL1 | |
| SCHEMBL10892031 | 0.81 | CYP1A2 (0.51) | RAB9ANPC1RECQLSMN1; SMN2L3MBTL1 | |
| SCHEMBL13607111 | 0.81 | RAB9A (0.57) | RAB9ANPC1RECQLSMN1; SMN2L3MBTL1 | |
| SCHEMBL10550058 | 0.80 | NPC1 (0.53) | RAB9ANPC1RECQLSMN1; SMN2L3MBTL1 | |
| SCHEMBL3803035 | 0.80 | NPC1 (0.64) | RAB9ANPC1RECQLSMN1; SMN2L3MBTL1 | |
| SCHEMBL15730801 | 0.78 | NPC1 (0.67) | RAB9ANPC1RECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL15708773 | 0.78 | NPC1 (0.67) | RAB9ANPC1RECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL13518783 | 0.77 | NPC1 (0.46) | RAB9ANPC1RECQLSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782570-A1 | SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE IN MEDICINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1997-07-09 | — | — | EP | disclosed |