Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | HTR2A | P28223 | 9/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 3/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.54 |
| ▸ | DRD1 | P21728 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | DRD5 | P21918 | 2/20 | 0.54 |
| ▸ | HTR1D | P28221 | 2/20 | 0.54 |
| ▸ | HTR1B | P28222 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.54 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808524 | 0.90 | DRD2 (0.54) | DRD2SLC6A4ACHEHTR2ADRD3 | |
| SCHEMBL8810867 | 0.86 | DRD2 (0.58) | DRD2SLC6A4ACHEHTR2ADRD3 | |
| SCHEMBL8808671 | 0.86 | DRD2 (0.60) | DRD2SLC6A4ACHEHTR2ADRD3 | |
| SCHEMBL8809113 | 0.85 | DRD2 (0.47) | DRD2SLC6A4ACHEHTR2ADRD3 | |
| SCHEMBL8810382 | 0.85 | DRD2 (0.57) | DRD2SLC6A4ACHEHTR2ADRD3 | |
| SCHEMBL8810725 | 0.85 | DRD2 (0.39) | DRD2SLC6A4ACHEHTR2ADRD3 | |
| SCHEMBL8812864 | 0.84 | HTR1D (0.45) | DRD2SLC6A4ACHEHTR2ADRD3 | |
| SCHEMBL8809492 | 0.82 | DRD2 (0.40) | DRD2SLC6A4ACHEHTR2ADRD3 | |
| SCHEMBL7294076 | 0.81 | DRD2 (0.66) | DRD2SLC6A4ACHEHTR2ADRD3 | |
| SCHEMBL8114624 | 0.80 | DRD2 (0.63) | DRD2SLC6A4ACHEHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794185-A1 | BICYCLIC THIAZOLE COMPOUND | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-10 | — | — | EP | claimed |
| EP-0794185-A1 | BICYCLIC THIAZOLE COMPOUND | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-10 | — | — | EP | disclosed |