Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809264 | 0.89 | ABCG2 (0.41) | MEN1KMT2AL3MBTL1ALDH1A1SMPD1 | |
| SCHEMBL8806572 | 0.88 | SMPD1 (0.44) | MEN1KMT2AKDM4EALDH1A1SMPD1 | |
| SCHEMBL4048156 | 0.81 | BCHE (0.54) | BCHEACHEMEN1KMT2AL3MBTL1 | |
| SCHEMBL4048160 | 0.80 | ABCB1 (0.58) | BCHEACHEMEN1KMT2AL3MBTL1 | |
| SCHEMBL8807951 | 0.75 | BCHE (0.45) | BCHEACHEMEN1KMT2AL3MBTL1 | |
| SCHEMBL8789541 | 0.75 | ABCG2 (0.65) | BCHEACHEMEN1KMT2AL3MBTL1 | |
| SCHEMBL8807050 | 0.75 | ABCB1 (0.45) | BCHEACHEMEN1KMT2AKDM4E | |
| SCHEMBL8789648 | 0.75 | ABCG2 (0.63) | BCHEACHEMEN1KMT2AKDM4E | |
| SCHEMBL8807941 | 0.75 | ABCB1 (0.57) | BCHEACHEMEN1KMT2AKDM4E | |
| SCHEMBL7168892 | 0.75 | CYP3A4 (0.55) | BCHEACHEMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663179-A | CAN SENSITIZE MULTIDRUG RESISTANT CANCER CELLS TO CHEMOTHERAPEUTIC AGENTS | LABORATOIRES GLAXO SA (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |