Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809286 | 0.87 | PARP1 (0.63) | PARP1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8809292 | 0.87 | PARP1 (0.63) | PARP1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8811843 | 0.86 | PARP1 (0.37) | PARP1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8686377 | 0.81 | PARP1 (0.50) | PARP1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8810705 | 0.79 | PARP1 (0.41) | PARP1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8685538 | 0.79 | PARP1 (0.63) | PARP1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8810770 | 0.78 | MEN1 (0.51) | PARP1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8686391 | 0.77 | KMT2A (0.51) | PARP1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8685437 | 0.76 | POLB (0.55) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8812780 | 0.76 | PARP1 (0.62) | PARP1KMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |