Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | NAT1 | P18440 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809292 | 1.00 | PARP1 (0.63) | PARP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8809303 | 0.87 | PARP1 (0.48) | PARP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8811840 | 0.86 | PARP1 (0.49) | PARP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8811841 | 0.86 | PARP1 (0.49) | PARP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1250177 | 0.83 | PARP1 (0.62) | PARP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12892101 | 0.83 | PARP1 (0.62) | PARP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1250179 | 0.83 | PARP1 (0.62) | PARP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8686373 | 0.81 | PARP1 (0.67) | PARP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8686376 | 0.81 | PARP1 (0.67) | PARP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8810698 | 0.80 | PARP1 (0.53) | PARP1MEN1KMT2ATTRAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |