Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.63 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.52 |
| ▸ | WNT3A | P56704 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | TDO2 | P48775 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15608471 | 0.86 | NPC1 (0.57) | RAB9ANPC1POLBKCNK3KCNK9 | |
| SCHEMBL3143842 | 0.85 | POLB (0.57) | RAB9ANPC1POLBKCNK3KCNK9 | |
| SCHEMBL29291422 | 0.85 | TP53 (0.64) | RAB9ANPC1KCNK3KCNK9GAA | |
| SCHEMBL8810715 | 0.84 | MRGPRX4 (0.55) | RAB9ANPC1POLBKCNK3KCNK9 | |
| SCHEMBL21483429 | 0.84 | POLB (0.56) | RAB9ANPC1POLBKCNK3KCNK9 | |
| SCHEMBL24239493 | 0.83 | KDM4E (0.58) | RAB9ANPC1POLBKCNK3KCNK9 | |
| SCHEMBL11578528 | 0.83 | NPC1 (0.68) | RAB9ANPC1POLBKCNK3KCNK9 | |
| SCHEMBL3484026 | 0.83 | RAB9A (0.66) | RAB9ANPC1GAATP53KDM4E | |
| SCHEMBL50229 | 0.83 | MAPT (0.64) | RAB9ANPC1KCNK3KCNK9GAA | |
| SCHEMBL29573531 | 0.83 | MAPT (0.64) | RAB9ANPC1KCNK3KCNK9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663179-A | CAN SENSITIZE MULTIDRUG RESISTANT CANCER CELLS TO CHEMOTHERAPEUTIC AGENTS | LABORATOIRES GLAXO SA (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |