Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808862 | 0.90 | KMT2A (0.45) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8815237 | 0.85 | MEN1 (0.36) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8811509 | 0.85 | PSEN1 (0.39) | LIPECHRM5PSEN1PSEN2APH1B | |
| SCHEMBL8810875 | 0.83 | ALDH1A1 (0.35) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8807376 | 0.83 | PSEN1 (0.40) | ALDH1A1KDM4EKMT2ACHRM5PSEN1 | |
| SCHEMBL8807489 | 0.83 | ALDH1A1 (0.35) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8810556 | 0.81 | ALDH1A1 (0.36) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9740515 | 0.81 | PSEN1 (0.42) | KDM4ELIPECHRM5PSEN1PSEN2 | |
| SCHEMBL8809308 | 0.80 | ALDH1A1 (0.37) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8810133 | 0.79 | ALDH1A1 (0.35) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350805-B1 | Benzopyran derivatives, processes for their preparation and their use and preparations containing the compounds | BEIERSDORF LILLY GMBH (DE) | 1997-04-16 | — | — | EP | disclosed |
| US-5096914-A | Hypotensive agents | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| US-5028711-A | Hypotensive Agents | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |