SCHEMBL8809555

SCHEMBL8809555

CCC(=O)CN1CCCC1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.48
ALDH1A1 P00352 6/20 0.45
HTT P42858 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
POLB P06746 2/20 0.43
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.40
MAOB P27338 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
NPC1 O15118 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
RAD52 P43351 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6220719 0.98 GAA (0.52) GAAALDH1A1HTTTDP1POLB
SCHEMBL9979988 0.98 GAA (0.52) GAAALDH1A1HTTTDP1POLB
SCHEMBL12233164 0.95
SCHEMBL19268642 0.90 TDP1 (0.47) GAAALDH1A1TDP1MAPTSMN1; SMN2
SCHEMBL16076280 0.90 TDP1 (0.47) GAAALDH1A1TDP1MAPTSMN1; SMN2
SCHEMBL23105019 0.85 HSD17B10 (0.44) GAAALDH1A1HTTTDP1POLB
SCHEMBL17092622 0.84 GAA (0.56) GAAALDH1A1HTTTDP1POLB
SCHEMBL10109058 0.83 MEN1 (0.47) GAAALDH1A1TDP1MAPTSMN1; SMN2
SCHEMBL10892602 0.81 GAA (0.54) GAAALDH1A1HTTTDP1POLB
SCHEMBL142180 0.81 GAA (0.61) GAAALDH1A1HTTTDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4691271-A2 TOBACCO TREATMENT British American Tobacco (Investments) Limited (GB) 2026-02-11 EP claimed
EP-3560356-B1 TOBACCO TREATMENT BRITISH AMERICAN TOBACCO INVESTMENTS LTD (GB) 2025-12-24 EP claimed
CN-109965339-B Tobacco treatment 英美烟草(投资)有限公司 2022-05-24 CN claimed
US-10966451-B2 Tobacco treatment BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) 2021-04-06 US claimed
EP-3560356-A1 TOBACCO TREATMENT British American Tobacco (Investments) Limited (GB) 2019-10-30 EP claimed
EP-3062640-B1 TOBACCO TREATMENT BRITISH AMERICAN TOBACCO INVESTMENTS LTD (GB) 2019-07-24 EP claimed
CN-109965339-A Tobacco processing 英美烟草(投资)有限公司 2019-07-05 CN claimed
US-20190174813-A1 TOBACCO TREATMENT BRITISH AMERICAN TABACCO PRESTADORA DE SERVICOS LTDA (BR) 2019-06-13 US claimed
US-10264813-B2 Tobacco treatment BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) 2019-04-23 US claimed
CN-105848502-B tobacco processing method 英美烟草(投资)有限公司 2019-04-16 CN claimed
US-20160270435-A1 TOBACCO TREATMENT BRITISH AMERICAN TABACCO PRESTADORA DE SERVICOS LTDA (BR) 2016-09-22 US claimed
CN-105848502-A Tobacco treatment 英美烟草(投资)有限公司 2016-08-10 CN claimed
JP-9140348-A None JP disclosed
EP-4691271-A2 TOBACCO TREATMENT British American Tobacco (Investments) Limited (GB) 2026-02-11 EP disclosed
EP-3560356-B1 TOBACCO TREATMENT BRITISH AMERICAN TOBACCO INVESTMENTS LTD (GB) 2025-12-24 EP disclosed
EP-4651738-A1 TOBACCO TREATMENT Nicoventures Trading Limited (GB) 2025-11-26 EP disclosed
US-20100221214-A1 LINKED DIBENZIMIDAZOLE DERIVATIVES ENANTA PHARMACEUTICALS, INC. 2010-09-02 US disclosed
WO-2010096462-A1 LINKED DIIMIDAZOLE DERIVATIVES ENANTA PHARMACEUTICALS, INC (US) 2010-08-26 WO disclosed
WO-2010091413-A1 LINKED DIBENZIMIDAZOLE DERIVATIVES ENANTA PHARMACEUTICALS, INC. (US) 2010-08-12 WO disclosed
JP-H09140348-A AGENT FOR IMPROVING FLAVOR AND SMELL QUALITY OF FOOD PERFUME AND IMPROVEMENT OF FLAVOR AND SMELL QUALITY OF FOOD PERFUME AND FOOD PERFUME COMPOSITION SHIONO KORYO KK 1997-06-03 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100221214-A1 LINKED DIBENZIMIDAZOLE DERIVATIVES EIF2AK2, NSUN2, ZC3HAV1 GAA 433/4885ALDH1A1 287/4885HTT 4662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.