Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17092622 | 0.97 | GAA (0.56) | GAAALDH1A1POLBMAPTHTT | |
| SCHEMBL142180 | 0.94 | GAA (0.61) | GAAALDH1A1POLBMAPTHTT | |
| Hydrochloric Acid SCHEMBL11699100 | 0.92 | GAA (0.58) | GAAALDH1A1POLBMAPTHTT | |
| SCHEMBL28374088 | 0.84 | ALDH1A1 (0.43) | GAAALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL4367541 | 0.83 | GAA (0.50) | GAAALDH1A1POLBMAPTHTT | |
| SCHEMBL4367538 | 0.83 | GAA (0.50) | GAAALDH1A1POLBMAPTHTT | |
| SCHEMBL1306310 | 0.81 | GAA (0.48) | GAAALDH1A1POLBMAPTHTT | |
| SCHEMBL6039586 | 0.81 | GAA (0.54) | GAAALDH1A1POLBMAPTHTT | |
| SCHEMBL8809555 | 0.81 | GAA (0.48) | GAAALDH1A1POLBMAPTHTT | |
| SCHEMBL16935758 | 0.79 | GAA (0.52) | GAAALDH1A1POLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096875-B1 | LITHIUM ALKOXIDE DIAMINES AS MODIFIERS FOR POLYMERIZATION OF DIENES USING LITHIUM-BASED INITIATORS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1986-10-08 | — | — | EP | disclosed |
| EP-0096875-A1 | Lithium alkoxide diamines as modifiers for polymerization of dienes using lithium-based initiators | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1983-12-28 | — | — | EP | disclosed |
| US-4401800-A | Lithium alkoxide diamines as modifiers for polymerization of dienes using lithium-based initiators | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1983-08-30 | — | — | US | disclosed |