Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HTR2C | P28335 | 12/20 | 0.50 |
| ▸ | HTR2B | P41595 | 12/20 | 0.50 |
| ▸ | HTR2A | P28223 | 8/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570611 | 0.97 | MEN1 (0.56) | MEN1KMT2AHTR2CHTR2BHTR2A | |
| SCHEMBL8574314 | 0.89 | HTR2C (0.60) | MEN1KMT2AHTR2CHTR2BHTR2A | |
| SCHEMBL8570870 | 0.88 | HTR2C (0.61) | MEN1KMT2AHTR2CHTR2BHTR2A | |
| SCHEMBL8567723 | 0.86 | HTR2C (0.62) | MEN1KMT2AHTR2CHTR2BHTR2A | |
| SCHEMBL8573905 | 0.86 | HTR2C (0.62) | MEN1KMT2AHTR2CHTR2BHTR2A | |
| SCHEMBL8574015 | 0.85 | HTR2C (0.51) | MEN1KMT2AHTR2CHTR2BHTR2A | |
| SCHEMBL8574255 | 0.85 | HTR2C (0.62) | MEN1KMT2AHTR2CHTR2BHTR2A | |
| SCHEMBL8572389 | 0.85 | HTR2C (0.64) | MEN1KMT2AHTR2CHTR2BHTR2A | |
| SCHEMBL8572332 | 0.85 | HTR2C (0.53) | MEN1KMT2AHTR2CHTR2BHTR2A | |
| SCHEMBL8569901 | 0.83 | HTR2C (0.62) | MEN1KMT2AHTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000872-A1 | 1,3,8-TRIAZA- AND 3,8-DIAZA-1-OXASPIRO(4,5)DECANE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 1997-01-09 | — | — | WO | disclosed |