Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.36 |
| ▸ | MMP2 | P08253 | 5/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP14 | P50281 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908998 | 0.81 | ANPEP (0.31) | ANPEP | |
| SCHEMBL6790942 | 0.76 | CA12 (0.42) | CA12MMP2CA14MMP8CA2 | |
| Phosphoric Acid SCHEMBL27687491 | 0.74 | — | — | |
| SCHEMBL9618024 | 0.72 | CA2 (0.32) | CA2CA4 | |
| SCHEMBL8810169 | 0.68 | CYP3A4 (0.40) | — | |
| Pimagedine SCHEMBL5537219 | 0.65 | CYP1A2 (0.39) | CA4 | |
| Phosphoric Acid SCHEMBL19458455 | 0.65 | CA4 (0.30) | CA4 | |
| SCHEMBL2222898 | 0.65 | — | — | |
| Pimagedine SCHEMBL11075497 | 0.65 | CYP1A2 (0.39) | CA4 | |
| Pimagedine SCHEMBL11075753 | 0.65 | CYP1A2 (0.39) | CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546548-B1 | Guanidinyl alkyl-1,1-bis phosphonic acid derivatives, process for their preparation and their use | HOECHST AG (DE) | 1997-05-02 | — | — | EP | claimed |