Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755490 | 0.81 | MEN1 (0.31) | KMT2AMEN1CACNA1BAPBA1PTGS1 | |
| SCHEMBL10402653 | 0.81 | ELANE (0.39) | ELANEKMT2AMEN1CACNA1BAPBA1 | |
| SCHEMBL10402651 | 0.81 | ELANE (0.39) | ELANEKMT2AMEN1CACNA1BAPBA1 | |
| SCHEMBL11153256 | 0.79 | ELANE (0.38) | ELANEKMT2AMEN1CACNA1BAPBA1 | |
| SCHEMBL11178071 | 0.78 | ELANE (0.37) | ELANEKMT2AMEN1CACNA1BAPBA1 | |
| SCHEMBL10403488 | 0.77 | ELANE (0.60) | ELANEKMT2AMEN1CACNA1BAPBA1 | |
| SCHEMBL10403487 | 0.77 | ELANE (0.60) | ELANEKMT2AMEN1CACNA1BAPBA1 | |
| SCHEMBL10402395 | 0.77 | ELANE (0.40) | ELANEKMT2AMEN1CACNA1BAPBA1 | |
| SCHEMBL10402352 | 0.77 | ELANE (0.39) | ELANEKMT2AMEN1CACNA1BAPBA1 | |
| SCHEMBL10403476 | 0.76 | ELANE (0.36) | ELANEKMT2AMEN1CACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232966-B1 | Process for the preparation of penem compounds and intermediates for this preparation | BEECHAM GROUP PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| EP-0232966-A1 | Process for the preparation of penem compounds and intermediates for this preparation | BEECHAM GROUP PLC (GB) | 1987-08-19 | — | — | EP | disclosed |