Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755485 | 0.82 | KMT2A (0.33) | MEN1KMT2APTGS1CACNA1BAPBA1 | |
| SCHEMBL9755483 | 0.82 | KMT2A (0.33) | MEN1KMT2APTGS1CACNA1BAPBA1 | |
| SCHEMBL9755503 | 0.81 | ELANE (0.39) | — | |
| SCHEMBL9755501 | 0.81 | ELANE (0.39) | — | |
| SCHEMBL8809929 | 0.81 | ELANE (0.38) | MEN1KMT2APTGS1CACNA1BAPBA1 | |
| SCHEMBL9637314 | 0.77 | ESR1 (0.38) | MEN1KMT2APTGS1MAPK1HSD17B10 | |
| SCHEMBL8668723 | 0.71 | CACNA1B (0.53) | MEN1KMT2ACACNA1BAPBA1MAPK1 | |
| SCHEMBL7348573 | 0.71 | CACNA1B (0.53) | MEN1KMT2ACACNA1BAPBA1MAPK1 | |
| SCHEMBL8668720 | 0.71 | CACNA1B (0.53) | MEN1KMT2ACACNA1BAPBA1MAPK1 | |
| SCHEMBL9538102 | 0.71 | ELANE (0.37) | MEN1KMT2APTGS1CACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991004977-A1 | NOVEL 2-SPIROCYCLOPROPYL CEPHALOSPORIN SULFONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LABORATORIES, INC. (CA) | 1991-04-18 | — | — | WO | disclosed |