Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 16/20 | 0.58 |
| ▸ | CAPNS1 | P04632 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809943 | 1.00 | CAPN1 (0.58) | CAPN1CAPNS1CASP1CASP3CASP7 | |
| SCHEMBL8810074 | 0.85 | CAPN1 (0.66) | CAPN1CAPNS1CASP1CASP3CTSK | |
| SCHEMBL8810052 | 0.85 | CAPN1 (0.66) | CAPN1CAPNS1CASP1CASP3CTSK | |
| SCHEMBL8808352 | 0.85 | CAPN1 (0.62) | CAPN1CAPNS1 | |
| SCHEMBL8808370 | 0.85 | CAPN1 (0.62) | CAPN1CAPNS1 | |
| SCHEMBL8407608 | 0.84 | CAPN1 (0.49) | CAPN1CAPNS1 | |
| SCHEMBL8407600 | 0.84 | CAPN1 (0.49) | CAPN1CAPNS1 | |
| SCHEMBL8808938 | 0.84 | CAPN1 (0.62) | CAPN1CAPNS1CASP1 | |
| SCHEMBL8808955 | 0.84 | CAPN1 (0.62) | CAPN1CAPNS1CASP1 | |
| SCHEMBL8809938 | 0.83 | CAPN1 (0.41) | CAPN1CAPNS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |