Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 11/20 | 0.49 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 4/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407608 | 1.00 | CAPN1 (0.49) | CAPN1CAPNS1ITGAVITGB3NR3C1 | |
| SCHEMBL8814671 | 0.94 | CAPN1 (0.45) | CAPN1CAPNS1ITGAVITGB3NR3C1 | |
| SCHEMBL8810089 | 0.87 | CAPN1 (0.49) | CAPN1CAPNS1ALDH1A1CYP2C19 | |
| SCHEMBL8810081 | 0.87 | CAPN1 (0.49) | CAPN1CAPNS1ALDH1A1CYP2C19 | |
| SCHEMBL8404264 | 0.86 | CAPN1 (0.55) | CAPN1CAPNS1ITGAVITGB3 | |
| SCHEMBL8404260 | 0.86 | CAPN1 (0.55) | CAPN1CAPNS1ITGAVITGB3 | |
| SCHEMBL8404242 | 0.84 | CAPN1 (0.54) | CAPN1CAPNS1 | |
| SCHEMBL8809943 | 0.84 | CAPN1 (0.58) | CAPN1CAPNS1 | |
| SCHEMBL8809931 | 0.84 | CAPN1 (0.58) | CAPN1CAPNS1 | |
| SCHEMBL8407604 | 0.84 | NR3C1 (0.39) | CAPN1CAPNS1NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | claimed |
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |