Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.94 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.94 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.64 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.64 |
| ▸ | BCHE | P06276 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154589 | 0.92 | LTA4H (0.79) | LTA4HEPHX2KDM4EALDH1A1OPRM1 | |
| SCHEMBL8814963 | 0.91 | LTA4H (0.78) | LTA4HEPHX2KDM4EALDH1A1OPRM1 | |
| SCHEMBL8499156 | 0.90 | LTA4H (0.82) | LTA4HEPHX2KDM4EALDH1A1OPRM1 | |
| SCHEMBL9081140 | 0.90 | LTA4H (0.82) | LTA4HEPHX2KDM4EALDH1A1OPRM1 | |
| SCHEMBL10399489 | 0.90 | KDM4E (0.84) | LTA4HEPHX2KDM4EALDH1A1BCHE | |
| SCHEMBL27688886 | 0.90 | KDM4E (0.84) | LTA4HEPHX2KDM4EALDH1A1BCHE | |
| SCHEMBL6540074 | 0.89 | LTA4H (0.76) | LTA4HEPHX2KDM4EALDH1A1OPRM1 | |
| SCHEMBL5947593 | 0.88 | LTA4H (0.79) | LTA4HEPHX2KDM4EALDH1A1OPRM1 | |
| SCHEMBL8497924 | 0.85 | LTA4H (0.79) | LTA4HEPHX2KDM4EALDH1A1BCHE | |
| SCHEMBL10098558 | 0.84 | LTA4H (0.68) | LTA4HEPHX2KDM4EALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |