Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808914 | 0.85 | MRGPRX4 (0.45) | MRGPRX4 | |
| SCHEMBL8807660 | 0.84 | — | — | |
| SCHEMBL8807145 | 0.83 | NPC1 (0.44) | MRGPRX4 | |
| SCHEMBL8810159 | 0.81 | MEN1 (0.44) | MRGPRX4 | |
| SCHEMBL8808400 | 0.81 | FFAR1 (0.44) | MRGPRX4 | |
| SCHEMBL8810273 | 0.75 | MRGPRX4 (0.43) | MRGPRX4 | |
| SCHEMBL8809995 | 0.75 | MEN1 (0.43) | MRGPRX4 | |
| SCHEMBL8809208 | 0.74 | MAOB (0.51) | MRGPRX4 | |
| SCHEMBL8807328 | 0.73 | MAPK14 (0.48) | — | |
| SCHEMBL8808247 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805802-A1 | SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS | RHONE-POULENC RORER LIMITED (GB) | 1997-11-12 | — | — | EP | claimed |
| WO-1996022978-A1 | SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS | RHONE POULENC RORER LIMITED (GB) | 1996-08-01 | — | — | WO | claimed |