Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809211 | 0.85 | MAOB (0.54) | MAOBMRGPRX4PTPN1 | |
| SCHEMBL8814943 | 0.83 | AR (0.37) | MAOBMRGPRX4 | |
| SCHEMBL12988735 | 0.83 | MAOB (0.70) | MAOBMRGPRX4PTPN1 | |
| SCHEMBL8808914 | 0.77 | MRGPRX4 (0.45) | MAOBMRGPRX4 | |
| SCHEMBL8896538 | 0.76 | PTPN1 (0.63) | MAOBMRGPRX4PTPN1 | |
| SCHEMBL8808917 | 0.76 | XDH (0.45) | MAOBMRGPRX4 | |
| SCHEMBL8133729 | 0.75 | CYP19A1 (0.47) | MAOBMRGPRX4 | |
| SCHEMBL3865512 | 0.75 | MAOB (0.77) | MAOBMRGPRX4 | |
| SCHEMBL7404465 | 0.75 | MAOB (0.63) | MAOBMRGPRX4 | |
| SCHEMBL6199191 | 0.75 | PTPN1 (0.59) | MAOBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805802-A1 | SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS | RHONE-POULENC RORER LIMITED (GB) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022978-A1 | SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS | RHONE POULENC RORER LIMITED (GB) | 1996-08-01 | — | — | WO | disclosed |