Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14365637 | 0.91 | PDE3B (0.40) | PDE3BPDE3APTGS2RPS6KA3AKR1C3 | |
| SCHEMBL10018710 | 0.88 | PTGS2 (0.40) | PDE3BPDE3APTGS2RPS6KA3AKR1C3 | |
| SCHEMBL18594796 | 0.82 | PDE9A (0.37) | PDE3BPDE3APTGS2RPS6KA3AKR1C3 | |
| SCHEMBL10014239 | 0.81 | PTGS2 (0.43) | PDE3BPDE3APTGS2RPS6KA3AKR1C3 | |
| SCHEMBL10024800 | 0.80 | PDE3B (0.42) | PDE3BPDE3APTGS2RPS6KA3AKR1C3 | |
| SCHEMBL4438303 | 0.80 | PDE3B (0.42) | PDE3BPDE3APTGS2RPS6KA3AKR1C3 | |
| SCHEMBL18973378 | 0.79 | PDE3B (0.40) | PDE3BPDE3APTGS2RPS6KA3AKR1C3 | |
| SCHEMBL13572725 | 0.79 | PDE3B (0.41) | PDE3BPDE3APTGS2RPS6KA3AKR1C3 | |
| SCHEMBL10018713 | 0.79 | PDE3B (0.41) | PDE3BPDE3APTGS2RPS6KA3AKR1C3 | |
| SCHEMBL19274153 | 0.78 | AKR1C3 (0.36) | PDE3BPDE3APTGS2RPS6KA3AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433923-A1 | CHLOROBENZENE DERIVATIVE, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM, AND OPTICAL ELEMENT | JNC Corporation (JP) | 2012-03-28 | — | — | EP | disclosed |