Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810449 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL8810455 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL5632939 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL7434157 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL7434354 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL17977269 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL8260150 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL7430439 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL7436135 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL8812717 | 0.75 | SOAT1 (0.44) | ALDH1A1KDM4EHPGDNPSR1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997013750-A1 | AZETIDINONES AND THEIR THERAPEUTIC USE AS CYTOKINE INHIBITORS | CHIROSCIENCE LIMITED (GB) | 1997-04-17 | — | — | WO | disclosed |