Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYB | P10242 | 13/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1752053 | 0.86 | MYB (0.70) | MYBMAPTALDH1A1CYP1A2LNPEP | |
| SCHEMBL8811031 | 0.85 | MYB (0.54) | MYBMAPTALDH1A1LNPEPGAA | |
| SCHEMBL8542128 | 0.85 | MYB (1.00) | MYBMAPTALDH1A1CYP1A2GAA | |
| SCHEMBL8809455 | 0.84 | MYB (0.53) | MYBMAPTALDH1A1LNPEPGAA | |
| SCHEMBL8813293 | 0.82 | MYB (0.55) | MYBMAPTALDH1A1CYP1A2GAA | |
| SCHEMBL8813284 | 0.81 | MYB (0.54) | MYBMAPTALDH1A1CYP1A2GAA | |
| SCHEMBL10275382 | 0.81 | MYB (0.74) | MYBMAPTALDH1A1CYP1A2LNPEP | |
| SCHEMBL10275379 | 0.81 | MYB (0.74) | MYBMAPTALDH1A1CYP1A2LNPEP | |
| SCHEMBL8808882 | 0.81 | MYB (0.58) | MYB | |
| SCHEMBL8809691 | 0.81 | MYB (0.60) | MYBMAPTALDH1A1CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618206-B1 | Pharmaceutical compounds | LILLY INDUSTRIES LTD (GB) | 1997-09-17 | — | — | EP | disclosed |
| US-5576325-A | TREATMENT OF IMMUNE DISEASES, RESTENOSIS, ENZYME INHIBITORS AND ANTISPASMODIC AGENTS | LILLY INDUSTRIES LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| US-5574034-A | TREATMENT OF IMMUNE DISEASES AND EXCESS CELL PROLIFERATION, ENZYME INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5571818-A | FOR TREATING IMMUNE DISEASES OR A DISEASE IN WHICH EXCESS CELL PROLIFERATION OR ENZYME RELEASE OCCUR | ELI LILLY AND COMPANY (US) | 1996-11-05 | — | — | US | disclosed |
| US-5514699-A | Pharmaceutical compounds | LILLY INDUSTRIES LIMITED (GB) | 1996-05-07 | — | — | US | disclosed |
| EP-0618206-A1 | Pharmaceutical compounds | LILLY INDUSTRIES LIMITED (GB) | 1994-10-05 | — | — | EP | disclosed |