Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.57 |
| ▸ | NPM1 | P06748 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690518 | 1.00 | PARP1 (0.57) | PARP1NPM1MEN1TTRAKR1B1 | |
| SCHEMBL8810605 | 0.90 | PARP1 (0.58) | PARP1NPM1MEN1TTRAKR1B1 | |
| SCHEMBL8686643 | 0.90 | PARP1 (0.58) | PARP1NPM1MEN1TTRAKR1B1 | |
| SCHEMBL8810595 | 0.88 | NPM1 (0.50) | PARP1NPM1KMT2ACNR2APP | |
| SCHEMBL8686629 | 0.88 | PARP1 (0.64) | PARP1MEN1TTRAKR1B1KMT2A | |
| SCHEMBL8813928 | 0.88 | PARP1 (0.64) | PARP1MEN1TTRAKR1B1KMT2A | |
| SCHEMBL8685962 | 0.87 | PARP1 (0.66) | PARP1MEN1TTRAKR1B1KMT2A | |
| SCHEMBL8685959 | 0.87 | PARP1 (0.66) | PARP1MEN1TTRAKR1B1KMT2A | |
| SCHEMBL8685201 | 0.87 | PARP1 (0.76) | PARP1NPM1MEN1TTRAKR1B1 | |
| SCHEMBL8808565 | 0.87 | PARP1 (0.76) | PARP1NPM1MEN1TTRAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |