Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808599 | 1.00 | SMPD1 (0.45) | SMPD1GAAMAPTMEN1KMT2A | |
| SCHEMBL8806156 | 1.00 | SMPD1 (0.45) | SMPD1GAAMAPTMEN1KMT2A | |
| SCHEMBL8810764 | 1.00 | SMPD1 (0.45) | SMPD1GAAMAPTMEN1KMT2A | |
| SCHEMBL8810151 | 0.97 | GAA (0.46) | SMPD1GAAMAPTMEN1KMT2A | |
| SCHEMBL8807029 | 0.91 | GAA (0.42) | SMPD1GAAMAPTMEN1KMT2A | |
| SCHEMBL8786359 | 0.90 | SMPD1 (0.47) | SMPD1GAAMAPTMEN1KMT2A | |
| SCHEMBL8785758 | 0.90 | SMPD1 (0.47) | SMPD1GAAMAPTMEN1KMT2A | |
| SCHEMBL8811077 | 0.90 | GAA (0.41) | SMPD1GAAMAPTMEN1KMT2A | |
| SCHEMBL8786558 | 0.89 | SMPD1 (0.42) | SMPD1GAAMAPTMEN1KMT2A | |
| SCHEMBL8883714 | 0.88 | MEN1 (0.50) | SMPD1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650960-B1 | Substituted heterocyclic carboxylic acid amide esters, their preparation and their us as medicaments | HOECHST AG (DE) | 1997-03-05 | — | — | EP | disclosed |
| EP-0650960-A1 | Substituted heterocyclic carboxylic acid amide esters, their preparation and their us as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-03 | — | — | EP | disclosed |