Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810151 | 0.92 | GAA (0.46) | GAAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8808599 | 0.90 | SMPD1 (0.45) | GAAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8810909 | 0.90 | SMPD1 (0.45) | GAAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8810764 | 0.90 | SMPD1 (0.45) | GAAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8882089 | 0.90 | GAA (0.44) | GAAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8806156 | 0.90 | SMPD1 (0.45) | GAAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8807029 | 0.87 | GAA (0.42) | GAAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8787448 | 0.85 | GAA (0.47) | GAAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8784539 | 0.84 | GAA (0.45) | GAAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8807374 | 0.83 | TRPV1 (0.38) | GAAMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650960-B1 | Substituted heterocyclic carboxylic acid amide esters, their preparation and their us as medicaments | HOECHST AG (DE) | 1997-03-05 | — | — | EP | disclosed |
| EP-0650960-A1 | Substituted heterocyclic carboxylic acid amide esters, their preparation and their us as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-03 | — | — | EP | disclosed |