Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 13/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411294 | 1.00 | PTGIR (0.57) | PTGIRTBXAS1HTTSMN1; SMN2HTR1A | |
| SCHEMBL8411295 | 0.89 | PTGIR (0.44) | PTGIRTBXAS1HTR1ASIGMAR1CFTR | |
| SCHEMBL8813608 | 0.88 | PTGIR (0.59) | PTGIRSMN1; SMN2 | |
| SCHEMBL8809666 | 0.88 | PTGIR (0.59) | PTGIRSMN1; SMN2 | |
| SCHEMBL8809040 | 0.83 | PTGIR (0.47) | PTGIRTBXAS1HTR1ASIGMAR1 | |
| SCHEMBL8810733 | 0.83 | PTGIR (0.47) | PTGIRTBXAS1HTR1ASIGMAR1 | |
| SCHEMBL8411299 | 0.82 | PTGIR (0.41) | PTGIRTBXAS1HTTSMN1; SMN2 | |
| SCHEMBL8810220 | 0.79 | PTGIR (0.41) | PTGIRTBXAS1HTTSMN1; SMN2 | |
| SCHEMBL8811692 | 0.79 | PTGIR (0.41) | PTGIRTBXAS1HTTSMN1; SMN2 | |
| SCHEMBL8520473 | 0.78 | PTGIR (0.89) | PTGIRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| US-5389666-A | Administering for treatment and prevention of thrombosis, arteriosclerosis, ischemic heart diseases, gastric ulcer or hypertension | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |