Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 15/20 | 0.59 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8813608 | 1.00 | PTGIR (0.59) | PTGIRPTGDR2PTGDRADRB3MEN1 | |
| SCHEMBL8813610 | 0.89 | PTGIR (0.45) | PTGIR | |
| SCHEMBL8411294 | 0.88 | PTGIR (0.57) | PTGIRSMN1; SMN2 | |
| SCHEMBL8810992 | 0.88 | PTGIR (0.57) | PTGIRSMN1; SMN2 | |
| SCHEMBL8812537 | 0.85 | PTGIR (0.39) | PTGIR | |
| SCHEMBL8812532 | 0.85 | PTGIR (0.39) | PTGIR | |
| SCHEMBL8813614 | 0.82 | PTGIR (0.43) | PTGIRPTGDR2PTGDR | |
| SCHEMBL8810733 | 0.80 | PTGIR (0.47) | PTGIRMEN1KMT2A | |
| SCHEMBL8809040 | 0.80 | PTGIR (0.47) | PTGIRMEN1KMT2A | |
| SCHEMBL8812792 | 0.78 | PTGIR (0.64) | PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| US-5389666-A | Administering for treatment and prevention of thrombosis, arteriosclerosis, ischemic heart diseases, gastric ulcer or hypertension | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |