Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 6/20 | 0.57 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.57 |
| ▸ | GRIA3 | P42263 | 6/20 | 0.57 |
| ▸ | GRIA4 | P48058 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099238 | 0.95 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL6790241 | 0.91 | GRIA1 (0.48) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL6785960 | 0.85 | GRIA1 (0.59) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6790702 | 0.83 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4HTR6 | |
| SCHEMBL6780488 | 0.81 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8807565 | 0.80 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7103867 | 0.80 | GRIA1 (0.59) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7100831 | 0.78 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4HTR6 | |
| SCHEMBL6783780 | 0.77 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6791392 | 0.77 | GRIA1 (0.64) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664807-B1 | QUINOXALINEDIONE DERIVATIVES AS EAA ANTAGONISTS | WARNER LAMBERT CO (US) | 1997-09-10 | — | — | EP | claimed |