Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | PARP1 | P09874 | 4/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811035 | 0.89 | TTR (0.45) | MEN1KMT2APARP1IGF1RTTR | |
| SCHEMBL8811029 | 0.89 | TTR (0.45) | MEN1KMT2APARP1IGF1RTTR | |
| SCHEMBL8811843 | 0.82 | PARP1 (0.37) | MEN1KMT2APARP1CSNK2A2CLK1 | |
| SCHEMBL8810705 | 0.81 | PARP1 (0.41) | MEN1KMT2APARP1CSNK2A2CLK1 | |
| SCHEMBL8691078 | 0.79 | PTPN1 (0.34) | KMT2AALDH1A1 | |
| SCHEMBL8811257 | 0.78 | MEN1 (0.40) | MEN1KMT2APARP1CSNK2A2CLK1 | |
| SCHEMBL8810448 | 0.75 | MEN1 (0.38) | MEN1KMT2APARP1CSNK2A2CLK1 | |
| SCHEMBL8685568 | 0.74 | KMT2A (0.45) | MEN1KMT2APARP1CSNK2A2CLK1 | |
| SCHEMBL8808805 | 0.73 | CA2 (0.37) | ALDH1A1GAAMAPT | |
| SCHEMBL8808814 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |