SCHEMBL8811050

SCHEMBL8811050

O=C(O)COc1cccc2c1CCC(CSc1nc(-c3ccccc3)c(-c3ccccc3)n1-c1ccccc1)C2

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 20/20 0.55
PTGDR Q13258 9/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9149888 1.00 PTGIR (0.55) PTGIRPTGDR
SCHEMBL8411304 0.92 PTGIR (0.53) PTGIRPTGDR
SCHEMBL8414301 0.85 PTGIR (0.56) PTGIRPTGDR
SCHEMBL8414372 0.83 PTGIR (0.56) PTGIRPTGDR
SCHEMBL8411306 0.80 PTGIR (0.41) PTGIRPTGDR
SCHEMBL8412778 0.79 PTGIR (0.55) PTGIRPTGDR
SCHEMBL8410505 0.77 PTGIR (0.59) PTGIRPTGDR
SCHEMBL8412019 0.76 PTGIR (0.65) PTGIRPTGDR
SCHEMBL8414275 0.75 PTGIR (0.54) PTGIRPTGDR
SCHEMBL8809968 0.75 PTGIR (0.59) PTGIRPTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0548949-B1 Fused benzeneoxyacetic acid derivatives ONO PHARMACEUTICAL CO (JP) 1997-09-17 EP claimed
EP-0548949-A2 Fused benzeneoxyacetic acid derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1993-06-30 EP claimed