Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124000 | 1.00 | HSD17B10 (0.33) | HSD17B10MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4435193 | 0.83 | CHRM2 (0.33) | CHRM2CHRM1CHRM3 | |
| SCHEMBL4440743 | 0.77 | CTSK (0.33) | MEN1ALDH1A1MAPTKMT2ACA1 | |
| SCHEMBL6487921 | 0.77 | MEN1 (0.51) | HSD17B10MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL6928427 | 0.77 | MEN1 (0.51) | HSD17B10MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2316321 | 0.75 | CA1 (0.41) | HSD17B10MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7294008 | 0.75 | NR1H2 (0.42) | MEN1ALDH1A1MAPTKMT2ACA1 | |
| SCHEMBL14763728 | 0.75 | CHRM2 (0.40) | MEN1ALDH1A1MAPTKMT2ACA1 | |
| SCHEMBL7284763 | 0.75 | CHRM2 (0.40) | MEN1ALDH1A1MAPTKMT2ACA1 | |
| SCHEMBL8329981 | 0.74 | CHRM2 (0.37) | HPGDCHRM2CHRM1CHRM3CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802190-A1 | Process and intermediates for preparing azepines | F. HOFFMANN-LA ROCHE AG (CH) | 1997-10-22 | — | — | EP | claimed |
| EP-0802190-A1 | Process and intermediates for preparing azepines | F. HOFFMANN-LA ROCHE AG (CH) | 1997-10-22 | — | — | EP | disclosed |