Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.45 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
| ▸ | MPC2 | O95563 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812572 | 0.91 | PPARG (0.50) | FFAR1PPARGMAPTPPARAALDH1A1 | |
| SCHEMBL8685830 | 0.91 | PPARG (0.47) | FFAR1PPARGMAPTPPARAALDH1A1 | |
| SCHEMBL8811924 | 0.90 | MAPT (0.55) | FFAR1PPARGMAPTPPARAALDH1A1 | |
| SCHEMBL8814118 | 0.90 | PPARG (0.45) | FFAR1PPARGMAPTPPARAALDH1A1 | |
| SCHEMBL8810752 | 0.90 | PPARG (0.45) | FFAR1PPARGMAPTPPARAALDH1A1 | |
| SCHEMBL8810415 | 0.89 | FFAR1 (0.43) | FFAR1PPARGMAPTPPARAALDH1A1 | |
| SCHEMBL8811959 | 0.89 | PPARG (0.43) | FFAR1PPARGMAPTPPARAALDH1A1 | |
| SCHEMBL8810658 | 0.88 | PPARG (0.42) | FFAR1PPARGMAPTPPARAALDH1A1 | |
| SCHEMBL8813433 | 0.88 | PPARG (0.52) | FFAR1PPARGMAPTPPARAALDH1A1 | |
| SCHEMBL8810910 | 0.88 | PPARG (0.52) | FFAR1PPARGMAPTPPARACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |