Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687694 | 0.92 | FFAR1 (0.41) | FFAR1PPARGPPARAMAPTCA2 | |
| SCHEMBL8810906 | 0.90 | FFAR1 (0.41) | FFAR1PPARGPPARAMAPTCA2 | |
| SCHEMBL8813771 | 0.90 | FFAR1 (0.41) | FFAR1PPARGPPARAMAPTCA2 | |
| SCHEMBL8811004 | 0.87 | FFAR1 (0.43) | FFAR1PPARGPPARACA2 | |
| SCHEMBL8810313 | 0.85 | FFAR1 (0.42) | FFAR1PPARGPPARA | |
| SCHEMBL8813371 | 0.84 | PPARG (0.41) | FFAR1PPARGPPARAMAPTCA2 | |
| SCHEMBL8685830 | 0.84 | PPARG (0.47) | FFAR1PPARGPPARAMAPTCA2 | |
| SCHEMBL8811053 | 0.83 | FFAR1 (0.42) | FFAR1PPARGPPARAMAPTCA2 | |
| SCHEMBL8687958 | 0.82 | PPARG (0.47) | FFAR1PPARGPPARAMAPTCA2 | |
| SCHEMBL8685774 | 0.82 | FFAR1 (0.50) | FFAR1PPARGPPARAMAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |