Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810504 | 0.89 | FFAR1 (0.41) | FFAR1PPARGMAPTCA2MAPK1 | |
| SCHEMBL8810461 | 0.87 | FFAR1 (0.44) | FFAR1PPARGMAPTCA2PPARA | |
| SCHEMBL8812828 | 0.86 | FFAR1 (0.39) | FFAR1PPARGMAPTCA2PPARA | |
| SCHEMBL8811280 | 0.83 | FFAR1 (0.42) | FFAR1PPARGMAPTCA2MAPK1 | |
| SCHEMBL8687694 | 0.81 | FFAR1 (0.41) | FFAR1PPARGMAPTCA2MAPK1 | |
| SCHEMBL8813771 | 0.81 | FFAR1 (0.41) | FFAR1PPARGMAPTCA2MAPK1 | |
| SCHEMBL8810906 | 0.81 | FFAR1 (0.41) | FFAR1PPARGMAPTCA2MAPK1 | |
| SCHEMBL8685380 | 0.79 | CA2 (0.43) | FFAR1PPARGMAPTCA2PPARA | |
| SCHEMBL8685830 | 0.79 | PPARG (0.47) | FFAR1PPARGMAPTCA2MAPK1 | |
| SCHEMBL8686495 | 0.79 | PPARG (0.44) | FFAR1PPARGMAPTCA2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167111-A | Thiazolidinedione derivatives, method for preparing derivatives and pharmaceutical compositions containing same | SENGA PHARMACEUTICAL LAB INC (JP) | 1997-12-10 | — | — | CN | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |