SCHEMBL8811366

SCHEMBL8811366

COc1cccc2c(=O)c(O)c(-c3cccc(O)c3O)oc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.58
ALDH1A1 P00352 4/20 0.58
CYP3A4 P08684 3/20 0.58
HPGD P15428 3/20 0.58
HSD17B10 Q99714 3/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
MAOA P21397 8/20 0.54
LMNA P02545 2/20 0.52
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
CYP1A1 P04798 6/20 0.51
CYP1A2 P05177 6/20 0.51
CYP1B1 Q16678 6/20 0.51
ABCG2 Q9UNQ0 2/20 0.48
ABCB1 P08183 1/20 0.48
MAPT P10636 2/20 0.48
ALOX15 P16050 2/20 0.47
TP53 P04637 1/20 0.47
ALOX12 P18054 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4627826 0.85 CYP1A1 (0.53) KDM4EALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL28546853 0.77 MAOA (0.73) KDM4EALDH1A1MAOALMNANPC1
SCHEMBL9665953 0.77 KDM4E (0.84) KDM4EALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL30346412 0.76 MAOA (0.79) KDM4EALDH1A1MAOALMNANPC1
SCHEMBL471860 0.74 NMUR2 (0.68) KDM4EALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL2179415 0.74 MAPT (0.60) KDM4EALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL13648962 0.74 ABCG2 (0.52) KDM4EALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL3898398 0.74 MAOA (0.56) MAOA
SCHEMBL7661006 0.73 MEN1 (0.63) KDM4EALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL4649481 0.73 KDM4E (1.00) KDM4EALDH1A1CYP3A4HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110846157-A Anti-aging, antibacterial and bacteriostatic soap composition and prepared soap 上海制皂有限公司 2020-02-28 CN disclosed
WO-1997000679-A1 BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS MEDICHEM RESEARCH, INC. (US) 1997-01-09 WO disclosed