Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197232 | 0.79 | ALDH1A1 (0.42) | SOAT1ALDH1A1PAOXGAAHSD17B10 | |
| SCHEMBL10534701 | 0.72 | CYP1A2 (0.59) | ALDH1A1PAOXGAAHSD17B10DGKA | |
| SCHEMBL6623769 | 0.72 | CYP1A2 (0.59) | ALDH1A1PAOXGAAHSD17B10DGKA | |
| SCHEMBL28663838 | 0.72 | CYP1A2 (0.59) | ALDH1A1PAOXGAAHSD17B10DGKA | |
| SCHEMBL6823809 | 0.72 | CYP1A2 (0.59) | ALDH1A1PAOXGAAHSD17B10DGKA | |
| SCHEMBL16022550 | 0.72 | CYP1A2 (0.59) | ALDH1A1PAOXGAAHSD17B10DGKA | |
| SCHEMBL6643452 | 0.72 | SOAT1 (0.61) | SOAT1ALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL28987086 | 0.72 | SOAT1 (0.61) | SOAT1ALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL11522479 | 0.72 | — | — | |
| SCHEMBL26695975 | 0.71 | ALDH1A1 (0.56) | SOAT1ALDH1A1PAOXGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |