SCHEMBL8811566

SCHEMBL8811566

O=C(O[C@H]1O[C@H](CO)C[C@H](O)[C@H]1O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGALS9 O00182 1/20 0.47
LGALS1 P09382 1/20 0.47
LGALS3 P17931 1/20 0.47
LGALS7; LGALS7B P47929 1/20 0.47
RNASE1 P07998 1/20 0.40
CHRNA7 P36544 2/20 0.40
MAOB P27338 1/20 0.38
HTR3E A5X5Y0 1/20 0.38
HTR3B O95264 1/20 0.38
HTR3A P46098 1/20 0.38
HTR3D Q70Z44 1/20 0.38
HTR3C Q8WXA8 1/20 0.38
APOBEC3A P31941 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
RAB9A P51151 2/20 0.37
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAPK1 P28482 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8811559 1.00 LGALS9 (0.47) LGALS9LGALS1LGALS3LGALS7; LGALS7BRNASE1
SCHEMBL8811557 0.81 LGALS9 (0.50) LGALS9LGALS1LGALS3LGALS7; LGALS7BRNASE1
SCHEMBL8815309 0.80 LGALS9 (0.46) LGALS9LGALS1LGALS3LGALS7; LGALS7BRNASE1
SCHEMBL23010225 0.78 NPC1 (0.49) CHRNA7NPC1SMN1; SMN2MAPK1HIF1A
SCHEMBL15368217 0.78 CHRNA7 (0.40) LGALS9LGALS1LGALS3LGALS7; LGALS7BCHRNA7
SCHEMBL20610934 0.78 NPC1 (0.49) CHRNA7NPC1SMN1; SMN2MAPK1HIF1A
SCHEMBL6570202 0.77 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL7141014 0.77 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL7144990 0.77 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL6570199 0.77 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996035700-A9 SACCHAROPEPTIDES AND DERIVATIVES THEREOF 1997-02-13 WO disclosed