Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.55 |
| ▸ | DPP4 | P27487 | 5/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.52 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | Q9HBH1 | 1/20 | 0.46 | |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811607 | 1.00 | DPP7 (0.55) | DPP7DPP9DPP8DPP4ERAP2 | |
| Hydrochloric Acid SCHEMBL9826997 | 0.92 | ERAP2 (0.49) | DPP7DPP9DPP8DPP4ERAP2 | |
| Hydrochloric Acid SCHEMBL9827159 | 0.92 | ERAP2 (0.49) | DPP7DPP9DPP8DPP4ERAP2 | |
| SCHEMBL2734071 | 0.92 | ERAP2 (0.49) | DPP7DPP9DPP8DPP4ERAP2 | |
| SCHEMBL31754261 | 0.90 | DPP7 (0.53) | DPP7DPP9DPP8DPP4ERAP2 | |
| SCHEMBL7324513 | 0.88 | BIRC2 (0.51) | DPP7DPP9DPP8DPP4ERAP2 | |
| SCHEMBL10781583 | 0.88 | PDF (0.46) | DPP7DPP9DPP8DPP4ERAP2 | |
| SCHEMBL9341044 | 0.88 | BIRC2 (0.57) | DPP7DPP9DPP8DPP4ERAP2 | |
| SCHEMBL27182882 | 0.88 | PDF (0.46) | DPP7DPP9DPP8DPP4ERAP2 | |
| SCHEMBL13496274 | 0.85 | ERAP2 (0.54) | DPP7DPP9DPP8DPP4ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602102-A | ADMINSTERING IN TREATMENT OF ORGAN ALLOGRAFT REJECTION | BOARD OF REGENTS, THE UNIV. OF TX SYSTEM (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0604416-A1 | IDENTIFYING MEMBRANOLYTIC COMPOUNDS AND PRECURSORS THEREOF | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-07-06 | — | — | EP | disclosed |
| WO-1993024634-A1 | DIPEPTIDYL PEPTIDASE-I, CLONING IT, AND THERAPEUTIC AGENTS CONTAINING INHIBITORS THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1993-12-09 | — | — | WO | disclosed |
| WO-1993005394-A1 | IDENTIFYING MEMBRANOLYTIC COMPOUNDS AND PRECURSORS THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1993-03-18 | — | — | WO | disclosed |