Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.59 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411192 | 0.89 | PTGIR (0.61) | PTGIRPTGDRPLA2G1BHTTL3MBTL1 | |
| SCHEMBL8813614 | 0.80 | PTGIR (0.43) | PTGIRPTGDRPLA2G1BHTTL3MBTL1 | |
| SCHEMBL8811346 | 0.80 | PTGIR (0.66) | PTGIRPTGDR | |
| SCHEMBL8811711 | 0.79 | PTGIR (0.86) | PTGIRPTGDRPTGDR2PLA2G2AALDH1A1 | |
| SCHEMBL8811350 | 0.79 | PTGIR (0.59) | PTGIRPTGDRPLA2G1BPTGDR2PLA2G2A | |
| SCHEMBL8814204 | 0.78 | PTGIR (0.53) | PTGIRPTGDR | |
| SCHEMBL8410896 | 0.75 | PTGIR (1.00) | PTGIRPTGDRPTGDR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8411186 | 0.70 | PTGIR (0.88) | PTGIR | |
| SCHEMBL8411299 | 0.69 | PTGIR (0.41) | PTGIRPTGDRPLA2G1BHTTPLA2G2A | |
| SCHEMBL8413362 | 0.69 | PTGIR (0.62) | PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5589496-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor agonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| US-5389666-A | Administering for treatment and prevention of thrombosis, arteriosclerosis, ischemic heart diseases, gastric ulcer or hypertension | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |