Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.61 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.36 |
| ▸ | DHPS | P49366 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 4/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.34 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812372 | 0.89 | PTGIR (0.59) | PTGIRALDH1A1L3MBTL1PLA2G1BPTGDR | |
| SCHEMBL8811350 | 0.83 | PTGIR (0.59) | PTGIRTBXAS1ALDH1A1PLA2G1BPTGDR | |
| SCHEMBL8411299 | 0.80 | PTGIR (0.41) | PTGIRTBXAS1DHPSALDH1A1PLA2G1B | |
| SCHEMBL8411186 | 0.79 | PTGIR (0.88) | PTGIRTBXAS1 | |
| SCHEMBL8413362 | 0.79 | PTGIR (0.62) | PTGIRPTGDR | |
| SCHEMBL8520476 | 0.79 | PTGIR (0.64) | PTGIRTBXAS1PLA2G1BPTGDR | |
| SCHEMBL8808707 | 0.77 | PTGIR (0.46) | PTGIRTBXAS1PTGDR | |
| SCHEMBL8410896 | 0.76 | PTGIR (1.00) | PTGIRTBXAS1ALDH1A1PTGDRSMN1; SMN2 | |
| SCHEMBL8809952 | 0.73 | PTGIR (0.72) | PTGIRTBXAS1ALDH1A1PLA2G1B | |
| SCHEMBL8811711 | 0.70 | PTGIR (0.86) | PTGIRALDH1A1PTGDRSMN1; SMN2PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | disclosed |